Endocrine Abstracts

Introduction: The clinical presentation of ectopic Cushing’s syndrome secondary to pheochromocytoma differs from the classic manifestations of these endocrinopathies separately. This cosecretion causes greater morbidity, requiring a complex preoperative preparation. We describe two clinical cases, a 46-year-old male with grade II overweight and a 65-year-old female with grade I obesity, both with a personal history of hypertension poorly controlled with 7 and 3 antihypert...

Precedents: Thirty-nine year old Woman. Classic phenylketonuria diagnosed for neonatal screening in Germany. Good adherence to the diet from the infancy, with good metabolic control. Not response to test with BH4.Pregnancy in 2007 with good controls of phenylalanine (Phe). Son with congenital cardiopathy.Evolution: In 2013 she planed new pregnancy, departing from very good controls (<4 mg/dl) and ingestion of 22–24 Phe&#14...

IntroductionThe term factitious thyrotoxicosis is defined as an excess of thyroid hormone in the body caused by the ingestion of exogenous thyroid hormone. It can be intentional, usually in patients with psychiatric disorders, or accidentally. Another possible cause is the inappropriate use of thyroid hormone for the treatment of obesity, depression or infertility.Case reportWe present the case of a 32-year-o...

IntroductionGastrointestinal adverse effects such as nausea and vomiting are widely described for GLP-1 receptor agonists (arGLP-1). We highlight Semaglutide, a drug that needs to start its administration at a reduced dose, to be able to increase the dose later with better tolerance and adherence of the patient. Not doing it this way can lead the patient to have serious adverse effects such as incoercible vomiting or profuse diarrhea that entails serious...

Introduction: New treatments of diabetes improve global metabolic status beyond glycemic control and achieve weight reduction in many patients.Case reports: We described four case reports to show GLP-1 agonists and dapaglifozin effects on metabolism and weight in patients with type 2 diabetes and obesity.Case 1 (Liraglutide): A 48-year-old man, hypertension, type 2 diabetes and extreme obesity. Baseline visit: treatment enalapril 2...

Objective: Prospective observational study in a group of pregnant patients affected by type 1 diabetes (T1DM), that are monitored by the Endocrinology and Pregnancy Unit.Material and Methods: Weevaluated 12 pregnant patients with T1DM in which a FreeStyle Libre Flash Glucose Monitoring Systemwas installed, in addition to their capillary glucose self-control (SMBG), over the past year 2019. Time above range (TAR), time in range (TIR) and time below range ...